Documentation about how to use them is covered in some detail in the online help In short, CWRES are conditional weighted residuals, a better alternative to WRES with the FOCE method in NONMEM. Don't forget to leave at least one blank line at the end of the model specification file. NONMEM automatically appends DV, PRED, WRES and RES unless NOAPPEND is specified. You can use code similar to the following to generate the tables you need. Strictly, only sdtab* is needed for basic goodness-of-fit functionality, but patab*, cotab*, catab* and the NONMEM input and output are recommended to get the full benefit from Xpose. Other variables you might need to have available to Xpose Parameter table, containing model parameters - THETAs, ETAs and EPSes Standard table file, containing ID, IDV, DV, PRED, IPRED, WRES, IWRES, RES, IRES, etc. Xpose looks for files according to the following pattern, where * is your run number: sdtab* If that doesn't work, check your naming convention. To specify the folder in which your files may be found (it can be any folder, not necessarily the one in the example). > setwd("/home/me/nmv/runs/") (UNIX/Linux) First, make sure R is looking in the right place. Xpose says it can't find any matching table files, but I have lots of them! You can (and should) install them from the R command line: You need the external libraries 'Hmisc' and 'gam' for Xpose to work. In addition: Warning message: there is no package called 'Hmisc' in: library(pkg, character.only = TRUE, logical = TRUE, lib.loc = lib.loc) I've installed Xpose as the instructions direct, but when I try to load it using library(xpose4), it says:Įrror: package 'Hmisc' could not be loaded We ask only that you share your modifications with the rest of us when they're done.ĭoes Xpose 4.0 work under Linux, UNIX or other non-Windows versions of R? Xpose 4.0 was written for R, and while the dialect of S used in R is similar to the one found in S-PLUS, they are not 100% compatible.īy all means. For example, if you want to know more about DV vs PRED plots and their options, typeĪt the R command line after loading Xpose.Īndrew Hooker can assist. We have updated the method for opening graphical devices to be consistent with the new methods used in R version 2.8.0.Īll Xpose 4.0 functions are documented within the R help system.
This release makes Xpose 4 compatible with R 2.8.0. We have updated xpose for NONMEM 7 as well as added functions for odd type (categorical, TTE, count) plots including VPCs. (no automatic printing from the function that created the plot). Multiple plots are returned as objects just like single plots Click here for more details.Ĭhanged the behaviour of. Note that, installation of Xpose has been simplified it is now available through the Comprehensive R Archive Network (CRAN). Xpose package xpose4generic version 4.3.3 releasedĪ new version of Xpose has been released.
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